PubMed · 16215702
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G Norman. 1998. On science, stories, quality and quantity.. https://doi.org/10.1023/a%3A1009776132401
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Precision oncology relies on integrating tumour fraction, variant allele frequency, clonal haematopoiesis of indeterminate potential assessment, pathogenicity, and clinical context into next-generation sequencing interpretation, enabling biologically informed and clinically meaningful treatment decisions while reducing the risk of overinterpreting nontumour or nonactionable genomic alterations.