Small intestinal submucosa intracardiac patch: an experimental study.

Michael Rosen; Eric E Roselli; Cristiano Faber; Norman B Ratliff; Jeffrey L Ponsky; Nicholas G Smedira

doi:10.1177/155335060501200307

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Small intestinal submucosa intracardiac patch: an experimental study.

Michael Rosen·Eric E Roselli·Cristiano Faber·Norman B Ratliff·Jeffrey L Ponsky·Nicholas G Smedira

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Abstract

In this experimental study, small intestinal submucosa was implanted as an atrial prosthesis in calves. Echocardiography and histology showed this to be an impermeable prosthesis that develops a neointimal nonthrombogenic surface making it safe for repair of defects in a low-pressure system. Further study with small intestinal submucosa in an intracardiac position is warranted.

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Animals Biopsy, Needle Cardiac Surgical Procedures Cattle Disease Models, Animal Graft Rejection Graft Survival Immunohistochemistry Intestinal Mucosa Intestine, Small Male Mitral Valve Risk Assessment Sensitivity and Specificity Surgical Flaps Comparative Study Journal Article

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Michael Rosen, Eric E Roselli, Cristiano Faber, Norman B Ratliff, Jeffrey L Ponsky, Nicholas G Smedira. 2005. Small intestinal submucosa intracardiac patch: an experimental study.. https://doi.org/10.1177/155335060501200307

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