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Human trophoblast function during the implantation process.

Elsebeth Staun-Ram·Eliezer Shalev
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Abstract

The implantation process involves complex and synchronized molecular and cellular events between the uterus and the implanting embryo. These events are regulated by paracrine and autocrine factors. Trophoblast invasion and migration through the uterine wall is mediated by molecular and cellular interactions, controlled by the trophoblast and the maternal microenvironment. This review is focused on the molecular constituents of the human trophoblast, their actions and interactions, including interrelations with the uterine endometrium.

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AnimalsCell Adhesion MoleculesChorionic GonadotropinCorticotropin-Releasing HormoneEmbryo ImplantationEpidermal Growth FactorExtracellular Matrix ProteinsFemaleHeparin-binding EGF-like Growth FactorHumansInsulin-Like Growth Factor Binding Protein 1IntegrinsIntercellular Signaling Peptides and ProteinsInterleukin-1Interleukin-6Leukemia Inhibitory FactorMatrix MetalloproteinasesMucin-1ProgesteroneProstaglandinsSerine EndopeptidasesTissue Inhibitor of MetalloproteinasesTransforming Growth Factor betaTrophoblastsTumor Necrosis Factor-alphaVascular Endothelial Growth Factor AJournal ArticleReview

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Elsebeth Staun-Ram, Eliezer Shalev. 2005-10-20. Human trophoblast function during the implantation process.. https://doi.org/10.1186/1477-7827-3-56

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