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A new anthelmintic cyclodepsipeptide, PF1022A.

T Sasaki·M Takagi·T Yaguchi·S Miyadoh·T Okada·M Koyama
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Abstract

The novel anthelmintic cyclodepsipeptide PF1022A was isolated from cultured mycelia of Mycelia Sterilia PF1022 (FERM BP-2671). It showed strong anthelmintic activities against Ascaridia galli in chickens. The structure of PF1022A was determined to be cyclo(D-lactyl-L-N-methylleucyl-D-3-phenyllactyl-L-N-meth ylleucyl-D-lactyl-L-N- methylleucyl-D-3-phenyllactyl-L-N-methylleucyl) by spectroscopic analyses and chemical studies.

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AnimalsAnthelminticsAscaridiaChickensDepsipeptidesMitosporic FungiPeptides, CyclicJournal Article

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T Sasaki, M Takagi, T Yaguchi, S Miyadoh, T Okada, M Koyama. 1992. A new anthelmintic cyclodepsipeptide, PF1022A.. https://doi.org/10.7164/antibiotics.45.692

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