Genetic, biochemical and structural approaches to talin function.

D R Critchley

doi:10.1042/bst0331308

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Genetic, biochemical and structural approaches to talin function.

D R Critchley

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Abstract

The cytoskeletal protein talin plays a key role in coupling the integrin family of cell adhesion molecules to the actin cytoskeleton. In this paper I present a brief review on talin and summarize our recent studies, in which we have taken both genetic and structural approaches to further elucidate the function of the protein.

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D R Critchley. 2005. Genetic, biochemical and structural approaches to talin function.. https://doi.org/10.1042/bst0331308

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