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Diffusion-weighted imaging with calculated apparent diffusion coefficient of enhancing extra-axial masses.

U Dorenbeck·I Q Grunwald·J Schlaier·S Feuerbach
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Abstract

BACKGROUND AND PURPOSE: Sometimes intracranial contrast-enhancing tumors like meningiomas, metastases, lymphomas, and schwannomas can mimic each other. It was the aim of the present study to investigate if intracranial contrast-enhancing lesions can be reliably differentiated with the help of diffusion-weighted imaging with calculated apparent diffusion coefficients (ADCs). METHODS: 29 patients (ages ranging from 22 to 82 years, mean age of 58.6 years) were included. Nine meningiomas, 7 metastases, 6 lymphomas, and 7 schwannomas were investigated. The ADC value in the lesions and in the perifocal edema was analyzed. RESULTS: For the lymphomas, the authors measured the lowest ADC values in the contrast-enhancing part (0.59 +/- 0.09 . 10(-3) mm2/sec). The meningiomas showed a mean ADC value of 0.98 +/- 0.18 . 10(-3) mm2/sec. The schwannomas and metastases showed higher ADC values of 1.33 +/- 0.28 . 10(-3) mm2/sec and 1.05 +/- 0.20 . 10(-3) mm2/sec. The authors saw a statistically significant difference between lymphomas, meningiomas, and metastases concerning the ADC values in the contrast-enhancing part. CONCLUSIONS: In spite of a small sample size and partly a wide range of values, the authors found statistically significant differences between meningiomas, metastases, and lymphomas concerning ADC values. Nevertheless, a differentiation of these lesions only with the help of ADC values seems questionable.

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AdultAgedAged, 80 and overBrain NeoplasmsDiffusion Magnetic Resonance ImagingEcho-Planar ImagingFemaleHumansMaleMeningeal NeoplasmsMeningiomaMiddle AgedJournal Article

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U Dorenbeck, I Q Grunwald, J Schlaier, S Feuerbach. 2005. Diffusion-weighted imaging with calculated apparent diffusion coefficient of enhancing extra-axial masses.. https://doi.org/10.1177/1051228405279991

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