Electrostatics in computational protein design.

Christina L Vizcarra; Stephen L Mayo

doi:10.1016/j.cbpa.2005.10.014

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Electrostatics in computational protein design.

Christina L Vizcarra·Stephen L Mayo

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Abstract

Catalytic activity and protein-protein recognition have proven to be significant challenges for computational protein design. Electrostatic interactions are crucial for these and other protein functions, and therefore accurate modeling of electrostatics is necessary for successfully advancing protein design into the realm of protein function. This review focuses on recent progress in modeling electrostatic interactions in computational protein design, with particular emphasis on continuum models.

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Computer Simulation Models, Theoretical Protein Conformation Proteins Static Electricity Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.Review

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Christina L Vizcarra, Stephen L Mayo. 2005-10-28. Electrostatics in computational protein design.. https://doi.org/10.1016/j.cbpa.2005.10.014

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