Managing and mining protein crystallization data.

Abdullah A Amin; Noel G Faux; Gustavo Fenalti; Geoffrey Williams; Adam Bernadou; Ben Daglish; Karen Keefe; Shayne Middleton; Joseph Rae; Kosmas Tetis; Ruby H P Law; Kate F Fulton; Jamie Rossjohn; James C Whisstock; Ashley M Buckle

doi:10.1002/prot.20776

PubMed · 16287081

Managing and mining protein crystallization data.

Abdullah A Amin·Noel G Faux·Gustavo Fenalti·Geoffrey Williams·Adam Bernadou·Ben Daglish·Karen Keefe·Shayne Middleton·Joseph Rae·Kosmas Tetis·Ruby H P Law·Kate F Fulton·Jamie Rossjohn·James C Whisstock·Ashley M Buckle

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Abstract

The crystallization of macromolecules remains a major bottleneck in structural biology. The routine screening of more than one thousand crystallization conditions and subsequent optimization by fine screening presents a challenge to conventional laboratory notebook keeping. In addition, the development of high-throughput robotic crystallization and imaging systems presents a pressing need for low-cost laboratory information management system (LIMS). Here we describe CLIMS2, a crystallization LIMS that features a simple, user-friendly graphical interface, allowing the storage, management, retrieval and mining of crystallization data. The CLIMS2 executable and documentation is freely available at http://clims.med.monash.edu.au.

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Computer Graphics Crystallization Databases, Protein Information Systems Macromolecular Substances Proteins Journal Article Research Support, Non-U.S. Gov't

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BibTeX RIS

Abdullah A Amin, Noel G Faux, Gustavo Fenalti, Geoffrey Williams, Adam Bernadou, Ben Daglish, Karen Keefe, Shayne Middleton, Joseph Rae, Kosmas Tetis, Ruby H P Law, Kate F Fulton, Jamie Rossjohn, James C Whisstock, Ashley M Buckle. 2006-01-01. Managing and mining protein crystallization data.. https://doi.org/10.1002/prot.20776

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