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PubMed · 16292865

A convenient method for synthesizing modified 4-nitrophenols.

Yumi Nakaike·Yoshio Kamijo·Satoshi Mori·Mina Tamura·Nagatoshi Nishiwaki·Masahiro Ariga
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Abstract

[reaction: see text] Beta-nitroenamine having a formyl group behaves as the synthetic equivalent of unstable nitromalonaldehyde upon treatment with ketones under basic conditions and leads to 2,6-disubstituted 4-nitrophenols. The present method is safer than the conventional one using sodium nitromalonaldehyde and enables the preparation of hitherto unknown nitrophenols.

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Molecular StructureNitrophenolsStereoisomerismJournal Article

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BibTeXRIS

Yumi Nakaike, Yoshio Kamijo, Satoshi Mori, Mina Tamura, Nagatoshi Nishiwaki, Masahiro Ariga. 2005-11-25. A convenient method for synthesizing modified 4-nitrophenols.. https://doi.org/10.1021/jo0516990

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