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Case-control analyses: Geneopardy!

Eric Jorgenson·Xin Liu·John S Witte
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Abstract

The case-control analyses group focused on a diverse set of questions, including study design, power, and analysis of case-control studies. Papers on study design examined various case-selection strategies, as well as ways to combine information from family- and population-based case-control data. The power of various approaches to case-control analyses was compared in several papers, while two papers chose to apply specific methods to analyzing the data. Two groups examined haplotype-related issues, including resolving un-phased haplotypes and comparing haplotype- and single-nucleotide polymorphism-based methods for analyzing data. Finally, one group examined the optimal number of markers for the genomic control approach to population stratification.

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AlcoholismCase-Control StudiesChromosome MappingCytogenetic AnalysisGenetic Predisposition to DiseaseGenotypeHumansLinkage DisequilibriumPhenotypePolymorphism, Single NucleotideQuantitative Trait LociTandem Repeat SequencesJournal Article

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Eric Jorgenson, Xin Liu, John S Witte. 2005. Case-control analyses: Geneopardy!. https://doi.org/10.1002/gepi.20114

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