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PubMed · 16352761

Bioluminescence imaging.

Ruxana T Sadikot·Timothy S Blackwell
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Abstract

Bioluminescence refers to the process of visible light emission in living organisms. Bioluminescence imaging is a powerful methodology that has been developed over the last decade as a tool for molecular imaging of small laboratory animals, enabling the study of ongoing biological processes in vivo. This form of optical imaging is low cost and noninvasive and facilitates real-time analysis of disease processes at the molecular level in living organisms. In this article, we provide a brief introduction to bioluminescence imaging technology and discuss its applications in mouse models of lung inflammation/injury, bacterial pneumonia, and tumor growth and metastasis.

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AnimalsDisease Models, AnimalLuciferasesLuminescenceLuminescent AgentsLung DiseasesMiceNF-kappa BJournal ArticleResearch Support, N.I.H., ExtramuralResearch Support, U.S. Gov't, Non-P.H.S.Review

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Ruxana T Sadikot, Timothy S Blackwell. 2005. Bioluminescence imaging.. https://doi.org/10.1513/pats.200507-067ds

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