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PubMed · 16381849

LOCATE: a mouse protein subcellular localization database.

J Lynn Fink·Rajith N Aturaliya·Melissa J Davis·Fasheng Zhang·Kelly Hanson·Melvena S Teasdale·Chikatoshi Kai·Jun Kawai·Piero Carninci·Yoshihide Hayashizaki·Rohan D Teasdale
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Abstract

We present here LOCATE, a curated, web-accessible database that houses data describing the membrane organization and subcellular localization of proteins from the FANTOM3 Isoform Protein Sequence set. Membrane organization is predicted by the high-throughput, computational pipeline MemO. The subcellular locations of selected proteins from this set were determined by a high-throughput, immunofluorescence-based assay and by manually reviewing >1700 peer-reviewed publications. LOCATE represents the first effort to catalogue the experimentally verified subcellular location and membrane organization of mammalian proteins using a high-throughput approach and provides localization data for approximately 40% of the mouse proteome. It is available at http://locate.imb.uq.edu.au.

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AnimalsDatabases, ProteinInternetMembrane ProteinsMiceProtein IsoformsProteomeUser-Computer InterfaceJournal ArticleResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't

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J Lynn Fink, Rajith N Aturaliya, Melissa J Davis, Fasheng Zhang, Kelly Hanson, Melvena S Teasdale, Chikatoshi Kai, Jun Kawai, Piero Carninci, Yoshihide Hayashizaki, Rohan D Teasdale. 2006-01-01. LOCATE: a mouse protein subcellular localization database.. https://doi.org/10.1093/nar%2Fgkj069

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