WormBase: better software, richer content.

Erich M Schwarz; Igor Antoshechkin; Carol Bastiani; Tamberlyn Bieri; Darin Blasiar; Payan Canaran; Juancarlos Chan; Nansheng Chen; Wen J Chen; Paul Davis; Tristan J Fiedler; Lisa Girard; Todd W Harris; Eimear E Kenny; Ranjana Kishore; Dan Lawson; Raymond Lee; Hans-Michael Müller; Cecilia Nakamura; Phil Ozersky; Andrei Petcherski; Anthony Rogers; Will Spooner; Mary Ann Tuli; Kimberly Van Auken; Daniel Wang; Richard Durbin; John Spieth; Lincoln D Stein; Paul W Sternberg

doi:10.1093/nar/gkj061

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PubMed · 16381915

WormBase: better software, richer content.

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Abstract

WormBase (http://wormbase.org), the public database for genomics and biology of Caenorhabditis elegans, has been restructured for stronger performance and expanded for richer biological content. Performance was improved by accelerating the loading of central data pages such as the omnibus Gene page, by rationalizing internal data structures and software for greater portability, and by making the Genome Browser highly customizable in how it views and exports genomic subsequences. Arbitrarily complex, user-specified queries are now possible through Textpresso (for all available literature) and through WormMart (for most genomic data). Biological content was enriched by reconciling all available cDNA and expressed sequence tag data with gene predictions, clarifying single nucleotide polymorphism and RNAi sites, and summarizing known functions for most genes studied in this organism.

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Animals Caenorhabditis elegans Caenorhabditis elegans Proteins DNA, Complementary Databases, Genetic Expressed Sequence Tags Genome, Helminth Genomics Internet Polymorphism, Single Nucleotide RNA Interference Software User-Computer Interface Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

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Erich M Schwarz, Igor Antoshechkin, Carol Bastiani, Tamberlyn Bieri, Darin Blasiar, Payan Canaran, Juancarlos Chan, Nansheng Chen, Wen J Chen, Paul Davis, Tristan J Fiedler, Lisa Girard, Todd W Harris, Eimear E Kenny, Ranjana Kishore, Dan Lawson, Raymond Lee, Hans-Michael Müller, Cecilia Nakamura, Phil Ozersky, Andrei Petcherski, Anthony Rogers, Will Spooner, Mary Ann Tuli, Kimberly Van Auken, Daniel Wang, Richard Durbin, John Spieth, Lincoln D Stein, Paul W Sternberg. 2006-01-01. WormBase: better software, richer content.. https://doi.org/10.1093/nar%2Fgkj061

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