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Epoxide hydrolases: structure, function, mechanism, and assay.

Michael Arand·Annette Cronin·Magdalena Adamska·Franz Oesch
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Abstract

Epoxide hydrolases are a class of enzymes important in the detoxification of genotoxic compounds, as well as in the control of physiological signaling molecules. This chapter gives an overview on the function, structure, and enzymatic mechanism of structurally characterized epoxide hydrolases and describes selected assays for the quantification of epoxide hydrolase activity.

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AnimalsBiological AssayEpoxide HydrolasesHumansInactivation, MetabolicMolecular StructureProtein FoldingRecombinant ProteinsStearic AcidsXenobioticsJournal ArticleReview

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Michael Arand, Annette Cronin, Magdalena Adamska, Franz Oesch. 2005. Epoxide hydrolases: structure, function, mechanism, and assay.. https://doi.org/10.1016/s0076-6879(05)00032-7

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