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PubMed · 16409004

Practical method for transforming alkynes into alpha-diketones.

Zhonghui Wan·Chauncey D Jones·David Mitchell·John Y Pu·Tony Y Zhang
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Abstract

[reaction: see text] Oxidation of alkynes to alpha-dicarbonyl derivatives through a convenient one-pot procedure via a Brønsted acid-promoted "hydration" and a DMSO-based oxidation sequence has been achieved in high yields. The scope and limitations of the reaction have also been investigated.

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AlkynesDimethyl SulfoxideIndicators and ReagentsKetonesModels, MolecularMolecular ConformationOxidation-ReductionJournal Article

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Zhonghui Wan, Chauncey D Jones, David Mitchell, John Y Pu, Tony Y Zhang. 2006-01-20. Practical method for transforming alkynes into alpha-diketones.. https://doi.org/10.1021/jo051793g

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