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Hyperforin: more than an antidepressant bioactive compound?

Miguel A Medina·Beatriz Martínez-Poveda·María I Amores-Sánchez·Ana R Quesada
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Abstract

Hyperforin is a lipophilic compound that is present in great amounts in St. John's wort and that has been described as the main responsible for the antidepressant effects of this medicinal plant. In the last few years, evidence has accumulated pointing to other different effects of hyperforin with potential pharmacological interest. They include other neurological effects, effects on inflammation, as well as antibacterial, antitumoral and antiangiogenic effects.

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Angiogenesis InhibitorsAnimalsAnti-Bacterial AgentsAnti-Inflammatory Agents, Non-SteroidalAntidepressive AgentsAntineoplastic Agents, PhytogenicApoptosisBridged Bicyclo CompoundsHumansHypericumPhloroglucinolTerpenesJournal ArticleResearch Support, Non-U.S. Gov'tReview

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Miguel A Medina, Beatriz Martínez-Poveda, María I Amores-Sánchez, Ana R Quesada. 2006-01-24. Hyperforin: more than an antidepressant bioactive compound?. https://doi.org/10.1016/j.lfs.2005.12.027

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