Solid-phase synthesis in the twenty-first century.

A Ganesan

doi:10.2174/138955706775197866

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PubMed · 16457628

Solid-phase synthesis in the twenty-first century.

A Ganesan

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Abstract

Solid-phase synthesis is a powerful tool for achieving high-throughput chemistry. This review discusses recent diverse examples from my group: the solid-phase synthesis of unsymmetrical guanidines, polymer-supported versions of cyclooctadiene and 9-BBN, a triflate-like linker, the synthesis of tetrahydro-beta-carbolines by the acyliminium Pictet-Spengler reaction, and a total synthesis of the antimycobacterial cyclic depsipeptide natural product kahalalide A.

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Alkadienes Boron Compounds Combinatorial Chemistry Techniques Guanidines Hydantoins Mesylates Molecular Structure Peptides, Cyclic Pharmaceutical Preparations Piperazines Tetrazoles Valine Valsartan Journal Article Review

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A Ganesan. 2006. Solid-phase synthesis in the twenty-first century.. https://doi.org/10.2174/138955706775197866

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