Development and virtual screening of target libraries.

Didier Rognan

doi:10.1016/j.jphysparis.2005.12.084

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Development and virtual screening of target libraries.

Didier Rognan

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Abstract

The concomitant development of in silico screening technologies and of three-dimensional information on therapeutically relevant macromolecular targets makes it possible to navigate in the structural proteome and to identify targets fulfilling user-defined queries. This review illustrates some in-house recent advances in the development of target libraries and how they can be browsed to unravel chemogenomic information.

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Animals Combinatorial Chemistry Techniques Computer Simulation Drug Design Drug Evaluation, Preclinical Humans Ligands Models, Molecular Molecular Structure Peptide Library Receptors, G-Protein-Coupled Structure-Activity Relationship Journal Article Research Support, Non-U.S. Gov't Review

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Didier Rognan. 2006-02-03. Development and virtual screening of target libraries.. https://doi.org/10.1016/j.jphysparis.2005.12.084

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