PubMed · 1646019
Why do c-type cytochromes exist? Reprise.
Abstract
An earlier paper (Wood, P.M. (1983) FEBS Lett. 164, 223-226) proposed that the covalent links that characterize c-type haem originated in order to prevent the haem being lost into the external medium. This is discussed in relation to Gram-negative and Gram-positive bacteria, cyanobacterial thylakoids and eukaryotes. The practical application is for unravelling complex electron transfer chains: c-type cytochromes may be assumed to be absent from the cytoplasm. Sulphate reducing bacteria provide the only confirmed exception to this rule. Examples of non-covalent haem at risk of being lost are considered. Analogies are drawn with flavin and pyrroloquinoline quinone as prosthetic groups.
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P M Wood. 1991-05-23. Why do c-type cytochromes exist? Reprise.. https://doi.org/10.1016/s0005-2728(05)80256-7
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