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Heredity: a prognostic factor for acne.

F Ballanger·P Baudry·J M N'Guyen·A Khammari·B Dréno
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Abstract

BACKGROUND: The role of heredity in acne severity and therapeutic response remains unclear. OBJECTIVE: A prospective epidemiologic study was performed to compare clinical and evolutive features of acne and response to treatment in 151 patients with acne with (A+) or without (A-) family history of acne. METHODS: A+ and A- patients were compared on clinical and therapeutic criteria. A+ patients were then distributed into subgroups (M+, F+, M+F+) following the origin of family history (father: F, mother: M). RESULTS: The clinical profile was similar in the A+ and A- populations. Acne occurred earlier and more often before puberty in the A+ population, in which oral treatments and relapse after isotretinoin were more frequent. Retentional lesions (number and extent) were more important in the M+ and M+F+ populations. CONCLUSION: This study confirms the importance of heredity as a prognostic factor for acne. Family history of acne is associated with earlier occurrence of acne, increased number of retentional lesions and therapeutic difficulties.

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Acne VulgarisAdolescentAdultAge of OnsetChildFemaleFollow-Up StudiesFranceGenetic Predisposition to DiseaseHeredityHumansMaleProspective StudiesRisk FactorsSeverity of Illness IndexComparative StudyJournal Article

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F Ballanger, P Baudry, J M N'Guyen, A Khammari, B Dréno. 2006. Heredity: a prognostic factor for acne.. https://doi.org/10.1159/000090655

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