Decoding complex Ca2+ signals through the modulation of Ras signaling.

Peter J Cullen

doi:10.1016/j.ceb.2006.02.012

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Decoding complex Ca2+ signals through the modulation of Ras signaling.

Peter J Cullen

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Abstract

Calcium (Ca(2+)) is a universal regulator of a wide variety of cellular processes. For such control to be achieved, information is encoded within spatial and temporal components of the underlying Ca(2+) signal. One pathway through which Ca(2+) signals are decoded is the Ras binary switch. Here I describe some recent advances that have shed light on how cells can decode the spatial and temporal aspects of Ca(2+) signals through the regulation of this important signalling switch.

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Animals Calcium Signaling Cell Membrane Golgi Apparatus Humans Intracellular Membranes Signal Transduction ras Proteins Journal Article Research Support, Non-U.S. Gov't Review

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Peter J Cullen. 2006-02-20. Decoding complex Ca2+ signals through the modulation of Ras signaling.. https://doi.org/10.1016/j.ceb.2006.02.012

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