Structural e-bioinformatics and drug design.

A J M Carpy; N Marchand-Geneste

doi:10.1080/10659360600560966

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Structural e-bioinformatics and drug design.

A J M Carpy·N Marchand-Geneste

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Abstract

Nowadays the in silico scenario for drug design is totally dependent on structural biology and structural bioinformatics. A myriad of free bioinformatics applications and services have been posted on the web. This mini-review mentions web sites that are useful in structure-based drug design. The information is given in a logical manner, following the drug design process i.e. characterization of a protein target, modelling the protein using sequence homology, optimization of the protein structure and finally docking of small ligands into the active site.

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Amino Acid Sequence Computational Biology Databases, Factual Drug Design Proteins Sequence Alignment Journal Article Review

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A J M Carpy, N Marchand-Geneste. 2006. Structural e-bioinformatics and drug design.. https://doi.org/10.1080/10659360600560966

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