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[Cerebral arterial infarction and diffusion tensor imaging].

S Rodrigo·C Oppenheim·E Touze·C Lamy·V Domigo·O Naggara·J L Mas·D Fredy·J F Meder
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Abstract

PURPOSE: Diffusion-weighted imaging (3 directions) and diffusion tensor imaging (9 directions) were compared for their sensitivity to detect ischemic lesion. MATERIALS AND METHODS: 41 patients (18 supposed transient ischemic attacks, 23 arterial stroke, MRI<or=48h) presenting with stroke syndrome were imaged using two diffusion sequences (3 directions, 2 excitations, acquisition time: 40 seconds and 9 directions, 1 excitation, acquisition time: 50 seconds, other parameters being identical). The following variables were compared (Wilcoxon test): number and extent of lesions, MRI signal and absolute ADC values, relative signal intensity and ADC ratio. Fractional anisotropy was measured within the principal lesion on the 9 directions sequence. RESULTS: 24 patients presented a lesion on both sequences. Four of them (including one TIA) had more lesions (<5 mm) on the 9 directions sequence than on the 3 directions sequence. Both sequences were normal for the 17 remaining patients (TIA=4, differential diagnosis=7, indeterminate=6). No significant difference was found for the other study parameters between 3 vs 9 directions sequences. There was a 10% decrease of the mean fractional anisotropy in ischemic lesion. CONCLUSION: By showing more lesions than standard diffusion-weighted imaging and providing quantitative anisotropy measurements, diffusion tensor imaging could replace the standard 3 directions diffusion-weighted sequence.

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AdultAgedAnisotropyCerebral InfarctionDiffusion Magnetic Resonance ImagingFemaleHumansMaleMiddle AgedSensitivity and SpecificityClinical TrialComparative StudyEnglish AbstractJournal Article

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S Rodrigo, C Oppenheim, E Touze, C Lamy, V Domigo, O Naggara, J L Mas, D Fredy, J F Meder. 2006. [Cerebral arterial infarction and diffusion tensor imaging].. https://doi.org/10.1016/s0150-9861(06)77228-5

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