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Multi-slice computer tomography of left ventricular function with automated analysis software in comparison with conventional ventriculography.

Martine Gilard·Pierre-Yves Pennec·Jean-Christophe Cornily·Ulric Vinsonneau·Gregoire Le Gal·Michel Nonent·Jacques Mansourati·Jacques Boschat
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Abstract

PURPOSE: To evaluate the accuracy of left ventricular volumetric and functional parameters from multi-slice computed tomography using automated analysis software, and to correlate results with those of invasive left ventriculography. MATERIALS AND METHODS: In 145 consecutive patients (mean age, 61 years+/-12) known or suspected to have coronary artery disease, a 16-channel multi-slice computed tomography (Philips Mx8000 IDT 16) was performed using a standard technique. Using short-axis secondary multi-slice computed tomography reformations, we determined end-diastolic and end-systolic left ventricular volumes and ejection fraction with a commercially available analysis software capable of automated contour detection. Conventional left ventriculography was performed according to standard techniques within the following 24 h. Bland-Altman analysis was performed to calculate the limits of agreement and systematic errors between multi-slice computed tomography and conventional left ventriculography. RESULTS: As determined by computer tomography, mean end-systolic (53+/-29 mL) left ventricular volumes had an acceptable correlation with conventional ventriculography (67+/-50 mL; r=0.74; p<0.001) and mean end-diastolic (119+/-33 mL) left ventricular volumes a poor correlation with conventional ventriculography measurements (154+/-69 mL; r=0.41). Left ventricular ejection fraction (57%+/-14 versus 55%+/-14 for conventional ventriculography; r=0.79) showed a very good correlation (p<0.001). Bland-Altman analysis showed acceptable limits of agreement (+/-9.2% for ejection fraction) without systematic errors. CONCLUSION: The use of a multi-slice computed tomography with an automatic calculation software has a good correlation with conventional ventriculography findings and could accurately assess left ventricular function, but should not be used for ventricular volumes, because of biased estimations.

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CineradiographyContrast MediaCoronary Artery DiseaseDiagnosis, Computer-AssistedDiagnostic Techniques, CardiovascularFeasibility StudiesFemaleHeart VentriclesHumansMaleMiddle AgedRadiographic Image EnhancementSoftwareTomography Scanners, X-Ray ComputedVentricular Function, LeftComparative StudyEvaluation StudyJournal Article

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Martine Gilard, Pierre-Yves Pennec, Jean-Christophe Cornily, Ulric Vinsonneau, Gregoire Le Gal, Michel Nonent, Jacques Mansourati, Jacques Boschat. 2006-03-27. Multi-slice computer tomography of left ventricular function with automated analysis software in comparison with conventional ventriculography.. https://doi.org/10.1016/j.ejrad.2006.02.010

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