The effect of radiation therapy on normal tissue function.

T J FitzGerald; Jesse Aronowitz; M Giulia Cicchetti; Graeme Fisher; Sidney Kadish; Y C Lo; Charles Mayo; Shelagh McCauley; Joshua Meyer; Richard Pieters; Alexandra Sherman

doi:10.1016/j.hoc.2006.01.005

PubMed · 16580561

The effect of radiation therapy on normal tissue function.

T J FitzGerald·Jesse Aronowitz·M Giulia Cicchetti·Graeme Fisher·Sidney Kadish·Y C Lo·Charles Mayo·Shelagh McCauley·Joshua Meyer·Richard Pieters·Alexandra Sherman

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Abstract

As more patients are treated for their primary malignancy with cure or increased disease-free intervals, injury to normal tissues will become more detectable and an important endpoint for study. Future protocols will probably be modified based on toxicity endpoints. In Hodgkin's disease, current protocols use response-based treatment strategies to limit therapy. The objective is to provide the same level of tumor control and follow normal tissue endpoints for outcome analysis. DVH analysis has improved the ability to analyze endpoint data for normal tissues. These image-guided platforms will provide the infrastructure needed to continue efforts in improving the delivery of radiation therapy.

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Dose-Response Relationship, Radiation Humans Neoplasms Radiation Injuries Radiosurgery Radiotherapy Planning, Computer-Assisted Journal Article Review

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T J FitzGerald, Jesse Aronowitz, M Giulia Cicchetti, Graeme Fisher, Sidney Kadish, Y C Lo, Charles Mayo, Shelagh McCauley, Joshua Meyer, Richard Pieters, Alexandra Sherman. 2006. The effect of radiation therapy on normal tissue function.. https://doi.org/10.1016/j.hoc.2006.01.005

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