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PubMed · 16580599

Host-pathogen systems biology.

Christian V Forst
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Abstract

Unlike traditional biological research that focuses on a small set of components, systems biology studies the complex interactions between a large number of genes, proteins and other elements of biological networks and systems. Host-pathogen systems biology examines the interactions between the components of two distinct organisms, either a microbial or viral pathogen and its animal host or two different microbial species in a community. With the availability of complete genomic sequences of various hosts and pathogens, together with breakthroughs in proteomics, metabolomics and other experimental areas, the investigation of host-pathogen systems on a multitude of levels of detail has come within reach.

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AnimalsBacterial Physiological PhenomenaComputer SimulationDrug DesignHumansImmune SystemInfectionsModels, BiologicalSignal TransductionSystems BiologyVirus DiseasesVirus Physiological PhenomenaJournal ArticleReview

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Christian V Forst. 2006. Host-pathogen systems biology.. https://doi.org/10.1016/s1359-6446(05)03735-9

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