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PubMed · 16582521

[Vascular development and cartilage formation].

Chisa Shukunami
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Abstract

During endochondral bone formation, resistance to vascular invasion changes in association with differentiation and maturation of chondrocytes. Just prior to chondrogenesis, the vasculature regresses and avascular cartilaginous bone primodia appear. The anti-angiogenic barrier of cartilage is acquired through coordinate interactions of extracellular matrices and angiogenesis inhibitors. In the process of vascular invasion into cartilage, angiogenesis stimulators and matrix degrading enzymes play important roles. In this review, the association of angiogenesis with endochondral bone formation will be discussed.

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Angiogenesis InhibitorsAnimalsCartilageCell DifferentiationChondrocytesChondrogenesisExtracellular MatrixHumansMatrix MetalloproteinasesNeovascularization, PhysiologicPlatelet Endothelial Cell Adhesion Molecule-1ProteinsVascular Endothelial Growth Factor AJournal ArticleReview

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Chisa Shukunami. 2006. [Vascular development and cartilage formation].. https://pubmed.ncbi.nlm.nih.gov/16582521/

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