Plasmodium post-genomics: better the bug you know?

Taco W A Kooij; Chris J Janse; Andrew P Waters

doi:10.1038/nrmicro1392

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PubMed · 16582929

Plasmodium post-genomics: better the bug you know?

Taco W A Kooij·Chris J Janse·Andrew P Waters

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Abstract

Since the publication of the sequence of the genome of Plasmodium falciparum, the major causative agent of human malaria, many post-genomic studies have been completed. Invaluably, these data can now be analysed comparatively owing to the availability of a significant amount of genome-sequence data from several closely related model species of Plasmodium and accompanying global proteome and transcriptome studies. This review summarizes our current knowledge and how this has already been--and will continue to be--exploited in the search for vaccines and drugs against this most significant infectious disease of the tropics.

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Animals Gene Expression Genome, Protozoan Plasmodium Proteome Comparative Study Journal Article Research Support, Non-U.S. Gov't Review

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Taco W A Kooij, Chris J Janse, Andrew P Waters. 2006. Plasmodium post-genomics: better the bug you know?. https://doi.org/10.1038/nrmicro1392

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