Sialic acid-specific lectins: occurrence, specificity and function.

F Lehmann; E Tiralongo; J Tiralongo

doi:10.1007/s00018-005-5589-y

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Sialic acid-specific lectins: occurrence, specificity and function.

F Lehmann·E Tiralongo·J Tiralongo

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Abstract

Sialic acids consist of a family of acidic nine-carbon sugars that are typically located at the terminal positions of a variety of glycoconjugates. Naturally occurring sialic acids show an immense diversity of structure, and this reflects their involvement in a variety of biologically important processes. One such process involves the direct participation of sialic acids in recognition events through specific interactions with lectins, a family of proteins that recognise and bind sugars. This review will present a detailed overview of our current knowledge regarding the occurrence, specificity and function of sialic acid-specific lectins, particularly those that occur in viruses, bacteria and non-vertebrate eukaryotes.

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Animals Bacteria Lectins N-Acetylneuraminic Acid Plants Substrate Specificity Viruses Journal Article Research Support, Non-U.S. Gov't Review

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F Lehmann, E Tiralongo, J Tiralongo. 2006. Sialic acid-specific lectins: occurrence, specificity and function.. https://doi.org/10.1007/s00018-005-5589-y

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