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Dragon Promoter Mapper (DPM): a Bayesian framework for modelling promoter structures.

Rajesh Chowdhary·Sin Lam Tan·R Ayesha Ali·Brent Boerlage·Limsoon Wong·Vladimir B Bajic
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Abstract

UNLABELLED: Dragon Promoter Mapper (DPM) is a tool to model promoter structure of co-regulated genes using methodology of Bayesian networks. DPM exploits an exhaustive set of motif features (such as motif, its strand, the order of motif occurrence and mutual distance between the adjacent motifs) and generates models from the target promoter sequences, which may be used to (1) detect regions in a genomic sequence which are similar to the target promoters or (2) to classify other promoters as similar or not to the target promoter group. DPM can also be used for modelling of enhancers and silencers. AVAILABILITY: http://defiant.i2r.a-star.edu.sg/projects/BayesPromoter/ CONTACT: vlad@sanbi.ac.za SUPPLEMENTARY INFORMATION: Manual for using DPM web server is provided at http://defiant.i2r.a-star.edu.sg/projects/BayesPromoter/html/manual/manual.htm.

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AlgorithmsBayes TheoremChromosome MappingComputer SimulationModels, GeneticModels, StatisticalPattern Recognition, AutomatedPromoter Regions, GeneticSequence Analysis, DNASoftwareUser-Computer InterfaceJournal Article

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Rajesh Chowdhary, Sin Lam Tan, R Ayesha Ali, Brent Boerlage, Limsoon Wong, Vladimir B Bajic. 2006-04-13. Dragon Promoter Mapper (DPM): a Bayesian framework for modelling promoter structures.. https://doi.org/10.1093/bioinformatics%2Fbtl125

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