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PubMed · 16676580

[Mitochondrial intermembrane space proteins in apoptosis process].

Jolanta Bednarek·Zofia M Kiliańska
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Abstract

Mitochondria, despite their function in cellular energy metabolism, play an important role in the apoptotic signaling pathways. These organelles in response to the death signal undergo changes resulting in the release of proteins which are essential to conduct apoptosis via mitochondrial pathway. This article is focused on the properties and functions of apoptogenic proteins released from the mitochondrial intermembrane space, i.e., caspases, cytochrome c, Smac/DIABLO, serine protease Omi/HtrA2, AIF and endonuclease G.

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AnimalsApoptosisEndonucleasesHumansMitochondriaMitochondrial ProteinsSignal TransductionEnglish AbstractJournal ArticleReview

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Jolanta Bednarek, Zofia M Kiliańska. 2005. [Mitochondrial intermembrane space proteins in apoptosis process].. https://pubmed.ncbi.nlm.nih.gov/16676580/

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