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Gaps in scientific knowledge for the post eradication world.

Philip Minor
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Abstract

There are significant gaps in the understanding of polio and polio vaccines which have programmatic importance even after 50 years of vaccine use. This paper considers four: the effect of strains used in the manufacture of IPV on safety and efficacy, the reasons for the safety of the Sabin strains, the nature and detection of long-term excreters of poliovirus and the basis for the cessation of virus excretion.

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HumansPoliomyelitisPoliovirusPoliovirus Vaccine, InactivatedSpecies SpecificityJournal Article

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Philip Minor. 2006-05-05. Gaps in scientific knowledge for the post eradication world.. https://doi.org/10.1016/j.biologicals.2006.02.006

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