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PubMed · 16700894

Polymeric core-shell nanoparticles for therapeutics.

Yi-Yan Yang·Yong Wang·Ross Powell·Peggy Chan
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Abstract

1. Nanobiotechnologies have recently attracted significant attention from chemists, biologists, engineers and pharmaceutical scientists. In particular, they have been widely applied to improve drug, protein/peptide and gene delivery. 2. This review presents recent advances in the field of drug, protein/peptide and gene delivery using natural and synthetic polymer nanoparticles and explains how polymeric nanoparticles are specifically designed to suit the needs for targeted delivery of small molecular drugs, proteins/peptides and genes. In addition, some of the challenges and prospects for these technologies are discussed.

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Administration, OralAnimalsDNADrug CarriersHumansHypoglycemic AgentsInsulinIntestinal AbsorptionNanoparticlesNanotechnologyNeoplasms, ExperimentalPolymersProteinsRNA, Small InterferingSolubilityTechnology, PharmaceuticalTransfectionVascular Endothelial Growth Factor Receptor-2Journal ArticleReview

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Yi-Yan Yang, Yong Wang, Ross Powell, Peggy Chan. Polymeric core-shell nanoparticles for therapeutics.. https://doi.org/10.1111/j.1440-1681.2006.04408.x

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