PubMed · 16701404
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William B Provine. 2005-06-02. Ernst Mayr, a retrospective.. https://doi.org/10.1016/j.tree.2005.05.009
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Precision oncology relies on integrating tumour fraction, variant allele frequency, clonal haematopoiesis of indeterminate potential assessment, pathogenicity, and clinical context into next-generation sequencing interpretation, enabling biologically informed and clinically meaningful treatment decisions while reducing the risk of overinterpreting nontumour or nonactionable genomic alterations.