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Profound lymphopenia and bacteraemia.

C A Hawkins·P Collignon·D N Adams·F J Bowden·M C Cook
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Abstract

Bacteraemia often carries a poor prognosis despite prompt antibiotic therapy and is associated with late morbidity and mortality that is difficult to explain. Here, we describe perisistent B- and T- cell lymphopenia in a cohort of patients with Gram-positive and Gram-negative bacteraemia. This suggests previously unrecognized mechanisms of subversion of immunity by pathogens and might explain the comorbidity of blood stream infection with bacteria.

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Anti-Bacterial AgentsB-LymphocytesBacteremiaHumansLeukocyte CountLymphopeniaProspective StudiesT-LymphocytesJournal Article

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C A Hawkins, P Collignon, D N Adams, F J Bowden, M C Cook. 2006. Profound lymphopenia and bacteraemia.. https://doi.org/10.1111/j.1445-5994.2006.01076.x

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