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PubMed · 16739973

Monitoring a complex medium fermentation with sample-sample two-dimensional FT-NIR correlation spectroscopy.

Ana P Ferreira·José C Menezes
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Abstract

The possibility of monitoring state transitions during the time course of a fermentation through the analysis of the on-line collected near-infrared (NIR) spectra with sample-sample two-dimensional correlation spectroscopy (SS-2DCoS) was investigated. SS-2DCoS has proved to be useful for extracting process information directly from the spectra collected on-line. The complexity of the system studied prevented the extraction of concentration profiles, but nevertheless, the application of SS-2DCoS enables the identification of fermentation state transitions due to metabolic and morphological changes of the microorganism.

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Cells, CulturedFermentationIndustrial MicrobiologyOnline SystemsSensitivity and SpecificitySpectroscopy, Fourier Transform InfraredStreptomycesTime FactorsComparative StudyJournal ArticleResearch Support, Non-U.S. Gov't

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Ana P Ferreira, José C Menezes. Monitoring a complex medium fermentation with sample-sample two-dimensional FT-NIR correlation spectroscopy.. https://doi.org/10.1021/bp0503991

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