Mitochondrial dynamics and Ca2+ signaling.

G Szabadkai; A M Simoni; K Bianchi; D De Stefani; S Leo; M R Wieckowski; R Rizzuto

doi:10.1016/j.bbamcr.2006.04.002

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Mitochondrial dynamics and Ca2+ signaling.

G Szabadkai·A M Simoni·K Bianchi·D De Stefani·S Leo·M R Wieckowski·R Rizzuto

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Abstract

Recent data shed light on two novel aspects of the mitochondria-Ca2+ liaison. First, it was extensively investigated how Ca2+ handling is controlled by mitochondrial shape, and positioning; a playground also of cell death and survival regulation. On the other hand, significant progress has been made to explore how intra- and near-mitochondrial Ca2+ signals modify mitochondrial morphology and cellular distribution. Here, we shortly summarize these advances and provide a model of Ca2+-mitochondria interactions.

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Animals Biological Evolution Calcium Signaling Endoplasmic Reticulum Humans Mitochondria Journal Article Research Support, Non-U.S. Gov't Review

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G Szabadkai, A M Simoni, K Bianchi, D De Stefani, S Leo, M R Wieckowski, R Rizzuto. 2006-04-20. Mitochondrial dynamics and Ca2+ signaling.. https://doi.org/10.1016/j.bbamcr.2006.04.002

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