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PubMed · 16768386

Diblock-type supramacromolecule via biocomplementary hydrogen bonding.

Atsushi Noro·Yutaka Nagata·Atsushi Takano·Yushu Matsushita
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Abstract

Control of nanostructure formation by a diblock-type supramacromolecule via biocomplementary hydrogen bonding has been achieved. Two different homopolymers, poly(4-trimethylsilylstyrene) and poly(styrene-d8), that are end-decorated with complementary oligonucleotides, i.e., thymidine phosphates and deoxyadenosine phosphates, were prepared by using the phosphoramidite method and blended successively. Association behavior in a blend solution was examined with NMR, and a cast bulk film obtained from the solution has been confirmed to show a nanophase-separated structure by transmission electron microscopy and X-ray scattering. Suppression of this nanostructure formation of a block-type supramacromolecule was also attained by adding a smaller agent as an inhibitor.

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Deoxyadenine NucleotidesDeuteriumHydrogen BondingMacromolecular SubstancesMicroscopy, Electron, TransmissionMolecular ConformationNanostructuresParticle SizePolystyrenesScattering, RadiationSensitivity and SpecificitySurface PropertiesThymine NucleotidesTrimethylsilyl CompoundsX-RaysJournal ArticleResearch Support, Non-U.S. Gov't

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Atsushi Noro, Yutaka Nagata, Atsushi Takano, Yushu Matsushita. 2006. Diblock-type supramacromolecule via biocomplementary hydrogen bonding.. https://doi.org/10.1021/bm0602280

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