PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 16768896

[Pain and depression].

Lise Gormsen·Troels Staehelin Jensen·Flemming Winther Bach·Raben Rosenberg
View original source ↗Export metadata ↓

Abstract

Pain and depression are often associated. The frequency of pain complaints in depressed patients is 13-100%. In general, depressed patients have a higher pain threshold than do controls, but lower and unchanged thresholds have also been observed. The frequency of depression in chronic pain patients is 1.5-100%. Pain etiology, short education, marital status, gender, psychiatric family history and unemployment are risk factors for depression. Possible mechanisms underlying the pathophysiology of depression and pain could be involvement of the monoamines (5-HT and NA) and the HPA axis.

Explore related subjects

Central Nervous SystemChronic DiseaseDepressionFemaleHumansMaleNociceptorsNorepinephrinePainPain ThresholdRisk FactorsSerotoninEnglish AbstractJournal ArticleReview

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

Lise Gormsen, Troels Staehelin Jensen, Flemming Winther Bach, Raben Rosenberg. 2006-05-15. [Pain and depression].. https://pubmed.ncbi.nlm.nih.gov/16768896/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2007

Controversies and challenges in defining the etiology and pathophysiology of restless legs syndrome.

Restless legs syndrome (RLS) can occur as a primary disorder, with no apparent cause other than a possible genetic predisposition, or as a secondary condition, most commonly related to iron deficiency, pregnancy, or end-stage renal disease. Recent studies have identified 2 different phenotypes of RLS based on age at onset of symptoms. Persons whose RLS symptoms start at an earlier age (<45 years) are more likely to have a family history of RLS and tend to have a more slowly progressive development of the disorder compared with individuals who have later onset of symptoms. In the past, our ability to determine either prevalence or population factors associated with increased occurrence of RLS has been limited. However, 4 different diagnostic criteria have been established. Familiarity with diagnostic criteria and clinical characteristics are essential for diagnosis and appropriate treatment, if required.

Central Nervous System↗