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Acanthamoeba keratitis after LASIK.

Ramamurthy Balasubramanya·Prashant Garg·Savitri Sharma·Geeta K Vemuganti
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Abstract

PURPOSE: To report a case of Acanthamoeba infection following LASIK. METHODS: A 20-year-old woman developed pain, redness, decreased vision, and corneal infiltrate in the right eye 15 days after bilateral LASIK. She did not use contact lenses postoperatively. Patient examination 3 months after surgery revealed a large, central, full-thickness corneal infiltrate with multiple satellite lesions in the right eye. Corneal scrapings were taken and the flap excised, and submitted for histopathologic examination. RESULTS: Microscopic examination of smears revealed Acanthamoeba cysts and non-nutrient agar showed a significant growth of Acanthamoeba. Histopathology examination of the excised flap demonstrated numerous Acanthamoeba cysts in tissue sections. The infiltrate was treated with a combination of topical polyhexamethylene biguanide, chlorhexidine, atropine sulfate, and oral itraconazole and resolved within 2 months. CONCLUSIONS: Laser in situ keratomileusis can be complicated by Acanthamoeba infection. Microbiologic evaluation is essential for accurate early diagnosis and treatment.

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AcanthamoebaAcanthamoeba KeratitisAdultAnimalsAntiprotozoal AgentsCorneaDiagnosis, DifferentialFemaleFollow-Up StudiesHumansKeratomileusis, Laser In SituRefractive Surgical ProceduresSurgical Wound InfectionCase ReportsJournal ArticleResearch Support, Non-U.S. Gov't

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Ramamurthy Balasubramanya, Prashant Garg, Savitri Sharma, Geeta K Vemuganti. 2006. Acanthamoeba keratitis after LASIK.. https://doi.org/10.3928/1081-597x-20060601-17

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