Hydra, a niche for cell and developmental plasticity.

Brigitte Galliot; Marijana Miljkovic-Licina; Renaud de Rosa; Simona Chera

doi:10.1016/j.semcdb.2006.05.005

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Hydra, a niche for cell and developmental plasticity.

Brigitte Galliot·Marijana Miljkovic-Licina·Renaud de Rosa·Simona Chera

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Abstract

The silencing of genes whose expression is restricted to specific cell types and/or specific regeneration stages opens avenues to decipher the molecular control of the cellular plasticity underlying head regeneration in hydra. In this review, we highlight recent studies that identified genes involved in the immediate cytoprotective function played by gland cells after amputation; the early dedifferentiation of digestive cells into blastema-like cells during head regeneration, and the early late proliferation of neuronal progenitors required for head patterning. Hence, developmental plasticity in hydra relies on spatially restricted and timely orchestrated cellular modifications, where the functions played by stem cells remain to be characterized.

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Animals Autophagy Cytoprotection Homeostasis Hydra Models, Biological Multipotent Stem Cells Phylogeny Regeneration Survival Journal Article Research Support, Non-U.S. Gov't Review

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Brigitte Galliot, Marijana Miljkovic-Licina, Renaud de Rosa, Simona Chera. 2006-05-27. Hydra, a niche for cell and developmental plasticity.. https://doi.org/10.1016/j.semcdb.2006.05.005

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