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High-speed electroseparations inside silica colloidal crystals.

Suping Zheng·Eric Ross·Michael A Legg·Mary J Wirth
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Abstract

Crystals made from 200 nm silica colloids are hardened and chemically modified with chlorodimethyloctadecylsilane for use in electrically driven, reversed-phase separations. A van Deemter plot reveals extremely narrow peak widths for the separation of a cationic hydrophobic dye, DiI, with both the A and C terms 10-fold smaller than those for a conventional HPLC column. Electrically driven separations are demonstrated to be achieved in less than 10 s for three dyes differing in hydrophobicity and also for three peptides differing in electrophoretic mobility. The results show that these media are promising for high-speed separations.

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ColloidsElectrochemistrySilicon DioxideJournal ArticleResearch Support, N.I.H., Extramural

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Suping Zheng, Eric Ross, Michael A Legg, Mary J Wirth. 2006-07-19. High-speed electroseparations inside silica colloidal crystals.. https://doi.org/10.1021/ja062676l

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