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PubMed · 16839471

Tizanidine distribution in a postmortem case.

Jason H Sklerov·Dawn E Cox·Karla A Moore·Barry Levine·David Fowler
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Abstract

The case of a 57-year-old white female who was found deceased at home by her husband is presented. A suicide note was found at the scene. No remarkable findings were observed at autopsy. Comprehensive toxicological analysis of the heart blood identified ethanol (0.16 g/dL), diazepam (1.1 mg/L), and tizanidine (2.3 mg/L). Blood concentrations of tizanidine following therapeutic use do not exceed 0.025 mg/L. The medical examiner ruled that the cause of death was combined ethanol and multiple drug intoxication, and the manner of death was suicide.

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Adrenergic alpha-AgonistsBileClonidineDrug InteractionsDrug OverdoseEthanolFemaleGastrointestinal ContentsHumansLiverMiddle AgedMuscle Relaxants, CentralSuicideCase ReportsJournal Article

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Jason H Sklerov, Dawn E Cox, Karla A Moore, Barry Levine, David Fowler. 2006. Tizanidine distribution in a postmortem case.. https://doi.org/10.1093/jat%2F30.5.331

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