Carbohydrate-based switch-on molecular sensor for Cu(II) in buffer: absorption and fluorescence study of the selective recognition of Cu(II) ions by galactosyl derivatives in HEPES buffer.

Nitin Kumar Singhal; Balaji Ramanujam; Vairamani Mariappanadar; Chebrolu Pulla Rao

doi:10.1021/ol061274f

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Carbohydrate-based switch-on molecular sensor for Cu(II) in buffer: absorption and fluorescence study of the selective recognition of Cu(II) ions by galactosyl derivatives in HEPES buffer.

Nitin Kumar Singhal·Balaji Ramanujam·Vairamani Mariappanadar·Chebrolu Pulla Rao

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Abstract

[graph: see text] 1-(Beta-D-galactopyranosyl-1'-deoxy-1'-iminomethyl)-2-hydroxynaphthalene (L1), possessing an ONO binding core, was found to be selective for Cu2+ ions in N-[2-hydroxyethyl]piperazine-N'-[2-ethanesulfonic acid] buffer, at concentrations < or = 580 ppb, at physiological pH by eliciting switch-on behavior, whereas the other ions, viz., Mg2+, Ca2+, Mn2+, Fe2+, Co2+, Ni2+, Zn2+, and Cd2+, caused no significant change in the fluorescence. Whereas the binding characteristics were ascertained by absorption spectroscopy, the species formed were shown by Q-TOF ES MS.

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Cations Copper Fluorescence Galactose HEPES Hydrogen-Ion Concentration Metals Molecular Structure Journal Article Research Support, Non-U.S. Gov't

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Nitin Kumar Singhal, Balaji Ramanujam, Vairamani Mariappanadar, Chebrolu Pulla Rao. 2006-08-03. Carbohydrate-based switch-on molecular sensor for Cu(II) in buffer: absorption and fluorescence study of the selective recognition of Cu(II) ions by galactosyl derivatives in HEPES buffer.. https://doi.org/10.1021/ol061274f

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