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PubMed · 16873410

Prestin and the cochlear amplifier.

Peter Dallos·Jing Zheng·Mary Ann Cheatham
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Abstract

In non-mammalian, hair cell-bearing sense organs amplification is associated with mechano-electric transducer channels in the stereovilli (commonly called stereocilia). Because mammals possess differentiated outer hair cells (OHC), they also benefit from a novel electromotile process, powered by the motor protein, prestin. Here we consider new work pertaining to this protein and its potential role as the mammalian cochlear amplifier.

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AnimalsAnion Transport ProteinsCochleaDeafnessHair Cells, Auditory, OuterHearingHumansMechanotransduction, CellularMiceMice, KnockoutMolecular Motor ProteinsProteinsSulfate TransportersJournal ArticleResearch Support, N.I.H., ExtramuralReview

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Peter Dallos, Jing Zheng, Mary Ann Cheatham. 2006-07-27. Prestin and the cochlear amplifier.. https://doi.org/10.1113/jphysiol.2006.114652

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