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PubMed · 16877017

Model analysis on alveolar-capillary O2 equilibration during exercise.

H Heller·K-D Schuster
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Abstract

The present article was aimed at determining the alveolar-capillary PO2 difference (deltaP(AcO2)) during exercise. The working hypothesis was that values of the pulmonary NO diffusing capacity can be used to calculate (deltaP(AcO2)) data on the basis of well-known laws of pulmonary gas exchange. For this purpose, we analysed the pertinent data of three studies performed on 35 healthy, non-athletic non-smokers of similar age at seven different exercise intensities. Calculated mean values of alveolar-capillary PO2 difference aggravated from deltaP(AcO2) at rest to (deltaP(AcO2))=18 mmHg at a performance capacity amounting to 90% of the maximum level. Regression analysis revealed (deltaP(AcO2))=0.31* (V O2/V O2 max)2 at a very high significance level (n=7, r=0.999, P<0.0000082). Due to the non-linear increase of (deltaP(AcO2)) with inclining O(2) consumption, our model analysis confirms the opinion that pulmonary diffusion decreasingly determines maximal aerobic power.

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ExerciseHumansModels, BiologicalOxygenPulmonary AlveoliJournal Article

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BibTeXRIS

H Heller, K-D Schuster. 2006-06-27. Model analysis on alveolar-capillary O2 equilibration during exercise.. https://doi.org/10.1016/j.niox.2006.06.006

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