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PubMed · 16880139

Branched DNA technology in molecular diagnostics.

Gregory J Tsongalis
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Abstract

Viral quantification or viral load testing has become part of the routine management of patients infected with HIV-1 or hepatitis C virus (HCV). There are currently several molecular technologies that are available for use in the clinical laboratory setting. Of these, only the branched DNA (bDNA) assays are FDA-approved for HIV-1 and HCV viral load testing. This signal amplification technology is built on a series of hybridization reactions that are highly amenable to full automation and thus lessen the amount of labor required to perform this type of analysis. This article provides a historical perspective of bDNA and its clinical applications.

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Acquired Immunodeficiency SyndromeDNA, ViralHIV-1HepacivirusHepatitis CHumansNucleic Acid Amplification TechniquesRNA, ViralViral LoadJournal Article

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Gregory J Tsongalis. 2006. Branched DNA technology in molecular diagnostics.. https://doi.org/10.1309/90bu6kdxanfln4rj

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