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[Tumor stem cells--a possible scenario].

László Kopper·Melinda Hajdú
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Abstract

More and more evidence support that tumors arise from somatic stem cells or from cells, either progenitors or differentiated ones, with the properties of stemness. It is a question whether all tumor cells have the capacity for self renewal and unlimited growth or only a fraction of them, i.e. the tumor stem cells. The concept is challenging, since the existence of tumor stem cells has an important practical consequence: only stem cells should be removed or stopped in order to control the tumor, while the other cells have temporary proliferative capacity.

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AnimalsBrain NeoplasmsBreast NeoplasmsCell MovementCell Transformation, NeoplasticDisease ProgressionFemaleHedgehog ProteinsHumansLeukemiaMaleNeoplasmsNeoplastic Stem CellsReceptors, NotchStem CellsTrans-ActivatorsWnt ProteinsEnglish AbstractJournal ArticleReview

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László Kopper, Melinda Hajdú. 2006-08-04. [Tumor stem cells--a possible scenario].. https://doi.org/huon.2006.50.2.0101

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