[Ionic selectivity of melittin-modified flat lipid bilayers].

R Z Sabirov; O V Krasil'nikov; E G Kostrzhevskaia

PubMed · 1692430

[Ionic selectivity of melittin-modified flat lipid bilayers].

R Z Sabirov·O V Krasil'nikov·E G Kostrzhevskaia

Abstract

It has been established in experiments with the bilayer lipid membranes (BLM) that at pH greater than 6.6 the melittin pores are cation-selective and at lower pH they are more selective by anions. The property of melittin pores is shown to be provided by the amino group of the N-terminal glycine residue. The selectivity of melittin-containing membranes may be controlled by the transmembrane potential, the cross-section of water pores being changed. The data obtained are explained within the alimethicine-like model.

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Bee Venoms Hydrogen-Ion Concentration Ion Channels Lipid Bilayers Melitten Membrane Potentials Permeability English Abstract Journal Article

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R Z Sabirov, O V Krasil'nikov, E G Kostrzhevskaia. [Ionic selectivity of melittin-modified flat lipid bilayers].. https://pubmed.ncbi.nlm.nih.gov/1692430/

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