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Tropical--parameter estimation and simulation of reaction-diffusion models based on spatio-temporal microscopy images.

Markus Ulrich·Constantin Kappel·Joel Beaudouin·Stefan Hezel·Jochen Ulrich·Roland Eils
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Abstract

UNLABELLED: Tropical is a software for simulation and parameter estimation of reaction-diffusion models. Based on spatio-temporal microscopy images, Tropical estimates reaction and diffusion coefficients for user-defined models. Tropical allows the investigation of systems with an inhomogeneous distribution of molecules, making it well suited for quantitative analyses of microscopy experiments such as fluorescence recovery after photobleaching (FRAP). AVAILABILITY: Tropical is available free of charge for academic use at http://www.dkfz.de/tbi/projects/modellingAndSimulationOfCelluarSystems/tropical.jsp after signing a material transfer agreement.

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AlgorithmsCell Physiological PhenomenaComputer SimulationDiffusionImage Interpretation, Computer-AssistedMicroscopy, FluorescenceModels, BiologicalProtein Interaction MappingSignal TransductionSoftwareJournal ArticleResearch Support, Non-U.S. Gov't

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Markus Ulrich, Constantin Kappel, Joel Beaudouin, Stefan Hezel, Jochen Ulrich, Roland Eils. 2006-08-29. Tropical--parameter estimation and simulation of reaction-diffusion models based on spatio-temporal microscopy images.. https://doi.org/10.1093/bioinformatics%2Fbtl456

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